Innate And Adaptive Immunity Compare And Contrast Essays

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Home»Pathology»Comparison of Innate and Adaptive Immunity

Comparison of Innate and Adaptive Immunity

Pathology12,404 Views

Innate Immunity
Adaptive Immunity
SpecificityNon-specificHighly specific
ActionFor structures shared by a group of microbesFor special antigens of microbial and non-microbial agents
Used againstFor microbesMicrobes and non-microbial substances called antigens
MemoryNo memoryLong term memory
ImprovementDoes not improve after exposure to organismImproves after each repeated exposure
Effective immediately after exposureYes –acts within minutesNo –requires several days before becoming effective
Self reactivityNoNo
Line of defense1st line as intrinsically presentDevelops after exposure
SpeedFaster responseSlower response
Sufficient in long runNot sufficient as children with severe combined immunodeficiency disease suffer from life threatening infectionsYes
Complement system activationVia alternative and lectin pathwaysActivated by classical pathway

1. Cells

  1. Monocytes
  2. Macrophages
  3. Neutrophils
  4. Natural killer cells
  1. Lymphocytes (T, B and plasma cells)
  2. Antigen presenting cells (macrophages, B and dendritic cells)
2. Blood proteinsComplement
 Anatomic and physiological barriers
  1. Skin
  2. Mucous membranes
  1. lymph nodes
  2. spleen
  3. mucosal associated lymphoid tissue


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